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Shivendra V Singh Selected Research

Ayurvedic Medicine (Siddha Medicine)

1/2017Disease Subtype-Independent Biomarkers of Breast Cancer Chemoprevention by the Ayurvedic Medicine Phytochemical Withaferin A.
11/2014Role of mitogen-activated protein kinases and Mcl-1 in apoptosis induction by withaferin A in human breast cancer cells.
1/2014Molecular targets and mechanisms of cancer prevention and treatment by withaferin a, a naturally occurring steroidal lactone.
8/2013Metabolic alterations in mammary cancer prevention by withaferin A in a clinically relevant mouse model.
7/2013Autophagy fails to alter withaferin A-mediated lethality in human breast cancer cells.
11/2012Withaferin A causes activation of Notch2 and Notch4 in human breast cancer cells.
8/2011Withaferin a suppresses estrogen receptor-α expression in human breast cancer cells.
3/2011Reactive oxygen species-dependent apoptosis by gugulipid extract of Ayurvedic medicine plant Commiphora mukul in human prostate cancer cells is regulated by c-Jun N-terminal kinase.
11/2010Withaferin A inhibits activation of signal transducer and activator of transcription 3 in human breast cancer cells.
1/2008Ayurvedic medicine constituent withaferin a causes G2 and M phase cell cycle arrest in human breast cancer cells.

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Shivendra V Singh Research Topics

Disease

112Neoplasms (Cancer)
03/2022 - 07/2002
69Prostatic Neoplasms (Prostate Cancer)
01/2021 - 07/2002
57Breast Neoplasms (Breast Cancer)
01/2022 - 11/2006
16Adenocarcinoma
10/2020 - 04/2005
11Neoplasm Metastasis (Metastasis)
01/2020 - 11/2008
10Carcinogenesis
01/2021 - 10/2002
8Carcinoma (Carcinomatosis)
01/2013 - 07/2002
5Lung Neoplasms (Lung Cancer)
04/2009 - 02/2003
4Prostatic Intraepithelial Neoplasia
01/2018 - 03/2009
4Pancreatic Neoplasms (Pancreatic Cancer)
01/2014 - 09/2004
3Ataxia Telangiectasia (Louis Bar Syndrome)
11/2019 - 06/2004
3Body Weight (Weight, Body)
01/2018 - 09/2008
3Squamous Cell Carcinoma of Head and Neck
02/2011 - 10/2003
3Weight Loss (Weight Reduction)
12/2009 - 04/2005
2Bone Resorption
01/2020 - 01/2018
2Hypoxia (Hypoxemia)
01/2019 - 11/2009
2Melanoma (Melanoma, Malignant)
01/2018 - 01/2017

Drug/Important Bio-Agent (IBA)

49Proteins (Proteins, Gene)FDA Link
03/2022 - 02/2003
27withaferin AIBA
01/2021 - 01/2008
26diallyl trisulfideIBA
03/2022 - 07/2004
25sulforaphaneIBA
01/2020 - 01/2004
25phenethyl isothiocyanate (PEITC)IBA
01/2018 - 07/2002
22benzyl isothiocyanateIBA
01/2019 - 10/2003
21Reactive Oxygen Species (Oxygen Radicals)IBA
01/2017 - 06/2004
13PhytochemicalsIBA
03/2022 - 10/2012
12AndrogensIBA
01/2021 - 05/2003
11Phosphotransferases (Kinase)IBA
11/2019 - 07/2002
10Transcription Factors (Transcription Factor)IBA
01/2022 - 04/2010
9CarcinogensIBA
10/2012 - 02/2003
8Androgen Receptors (Androgen Receptor)IBA
10/2019 - 08/2007
8IsothiocyanatesIBA
01/2016 - 05/2003
7RNA (Ribonucleic Acid)IBA
03/2022 - 01/2018
7Messenger RNA (mRNA)IBA
01/2021 - 02/2003
7LactonesIBA
10/2020 - 01/2014
7Biomarkers (Surrogate Marker)IBA
05/2017 - 04/2011
6Phenobarbital (Luminal)FDA Link
03/2022 - 03/2020
6Fatty Acids (Saturated Fatty Acids)IBA
01/2021 - 05/2017
6Estrogen ReceptorsIBA
01/2020 - 08/2011
6Antineoplastic Agents (Antineoplastics)IBA
11/2015 - 10/2002
6Cadherins (E-Cadherin)IBA
04/2014 - 12/2009
6STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
10/2012 - 04/2010
5Checkpoint Kinase 1IBA
11/2019 - 08/2005
5Biological ProductsIBA
01/2018 - 11/2009
5honokiolIBA
09/2016 - 10/2007
5VimentinIBA
06/2015 - 07/2011
5Histones (Histone)IBA
01/2014 - 01/2004
5pregna-4,17-diene-3,16-dione (guggulsterone)IBA
03/2011 - 11/2005
5diallyl disulfide (diallyl disulphide)IBA
04/2009 - 10/2002
4Methylnitrosourea (N-Methyl-N-nitrosourea)IBA
03/2022 - 01/2017
4EnzymesIBA
01/2021 - 11/2004
4dehydroabietylamineIBA
01/2021 - 01/2017
4Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
11/2014 - 07/2002
4JNK Mitogen-Activated Protein KinasesIBA
11/2014 - 07/2004
4Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
01/2014 - 01/2004
4DNA (Deoxyribonucleic Acid)IBA
06/2012 - 01/2004
4CaspasesIBA
11/2007 - 01/2004
47,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxideIBA
11/2007 - 02/2003
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2020 - 03/2007
3Lactic Acid (Lactate)FDA LinkGeneric
06/2020 - 01/2018
3LeptinIBA
03/2020 - 03/2011
3Cisplatin (Platino)FDA LinkGeneric
11/2019 - 01/2008
3Nonesterified Fatty Acids (NEFA)IBA
10/2019 - 05/2017
3Electron Transport Complex III (Coenzyme Q-Cytochrome-c Reductase)IBA
01/2019 - 10/2008
3Adenosine Triphosphate (ATP)IBA
01/2018 - 08/2012
3zerumboneIBA
10/2017 - 11/2012
3Estrogens (Estrogen)FDA Link
11/2014 - 09/2008
3Apoptosis Regulatory ProteinsIBA
11/2014 - 10/2003
3Protein Isoforms (Isoforms)IBA
08/2013 - 05/2008
3DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA
08/2012 - 11/2006
3guggulu extractIBA
03/2011 - 11/2009
3Erlotinib Hydrochloride (CP 358,774)FDA Link
02/2011 - 11/2009
3Interleukin-6 (Interleukin 6)IBA
11/2010 - 04/2010
3allyl sulfideIBA
04/2009 - 07/2004
3Benzo(a)pyreneIBA
11/2007 - 10/2002
3CDC2 Protein Kinase (Protein p34cdc2)IBA
07/2007 - 05/2004
3Cyclin B1IBA
07/2007 - 10/2003
3Checkpoint Kinase 2IBA
05/2007 - 06/2004
2ChromatinIBA
01/2021 - 10/2020
2Glucose (Dextrose)FDA LinkGeneric
06/2020 - 01/2019
2Diphosphonates (Bisphosphonates)IBA
01/2020 - 01/2018
2DenosumabFDA Link
01/2020 - 01/2018
2ATP Citrate (pro-S)-Lyase (Citrate Synthase, ATP)IBA
10/2019 - 01/2018
2LipidsIBA
10/2019 - 10/2017
2Pyruvic Acid (Pyruvate)IBA
01/2019 - 01/2018
2Oxygen (Dioxygen)IBA
01/2019 - 08/2007
2LigandsIBA
10/2018 - 01/2018
2Fatty Acid Synthases (Fatty Acid Synthase)IBA
01/2018 - 05/2017
2Acetyl-CoA CarboxylaseIBA
01/2018 - 05/2017
2Phospholipids (Phosphatides)FDA LinkGeneric
01/2018 - 05/2017
2Cytochromes c (Cytochrome c)IBA
01/2017 - 06/2006
2CytokinesIBA
01/2017 - 01/2016
2Aldehyde Dehydrogenase 1 FamilyIBA
11/2016 - 06/2016
2Epithelial Cell Adhesion MoleculeIBA
06/2016 - 08/2013
2Glutathione Transferase (Glutathione S-Transferase)IBA
01/2016 - 11/2004
2Amyloid Precursor Protein Secretases (beta-Secretase)IBA
02/2015 - 08/2012

Therapy/Procedure

29Chemoprevention
01/2021 - 03/2007
11Therapeutics
01/2021 - 01/2004
10Ayurvedic Medicine (Siddha Medicine)
01/2017 - 01/2008
7Oral Administration
03/2020 - 04/2005
4Castration
01/2021 - 01/2018